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Within endosomal vesicles, Fe 3+ undergoes six-transmembrane epithelial antigen of prostate 3 (STEAP3)-catalyzed reduction to Fe 2+ , subsequently exported to cytosol via divalent metal transporter 1 (DMT1) ( 2+ complexes are sequestered in the labile iron pool (LIP) through ferritin binding

Cancer chemotherapy based on targeting of cytotoxic peptide conjugates to their receptors on tumors

Meena M, Divyanshu K, Kumar S, Swapnil P, Zehra A, Shukla V, Upadhyay RS (2019) Regulation of L-proline biosynthesis, signal transduction, transport, accumulation and its vital role in plants during variable environmental conditions

In one study, MOTS-c significantly enhanced physical performance and running time (approximately 12 percent to 15 percent increase) in mice of all ages, suggesting it can confer exercise benefits without physical activity