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A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself

Doctors may recommend starting at the lower end of the dosing range (e.g., 0.31 mg) or extending the interval between treatments in cases of significant renal impairment

Journal of Molecular Medicine, 95(3), 323-333

Use the formula: V draw = D anchor V water M anchor D anchor is your target dose in mg, V water is the BAC water volume you reconstitute with in mL, and M anchor is the anchor compound mass in the vial in mg