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Regulatory effects of hawthorn polyphenols on hyperglycemic, inflammatory, insulin resistance responses, and alleviation of aortic injury in type 2 diabetic rats

Brien JF, Loomis CW

The latter is a GSH-dependent monomeric enzyme that plays a role in protecting Treg cells from iron-dependent lipid peroxidation-mediated death, whose absence disrupts Treg cell mitochondrial homeostasis and increases IL-1 production (137)

Concurrently, they also determined that THC significantly restrained cell growth by instigating mitochondrial-mediated apoptosis and inducing G2/M cell cycle arrest in MCF-7 cells [67]