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APOE4 carriers display decreased levels of antioxidative stress response proteins such as superoxide dismutase 2 (SOD2) and forkhead-box protein O3a (Foxo3a) compared to non- APOE4 carriers

Brain cells produced Cys-SSH and GSSH but not their polysulfide counterparts Cys-SS n H and GSS n H (Fig

Enhancements of dopamine bio-synthesis as estimated fi'om HVA concentration in CSF correlate withCSF tyrosine (C), Increases in the biosynthesis of dopamine and serotonin as measured by increased CSF concentrations of HVA and5-HIAA correlate with dietary tyrosine supplement (D)

Epsilon glutathione transferases possess a unique class-conserved subunit interface motif that directly interacts with glutathione in the active site