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Description

This interaction is part of a coevolutionary relationship between hosts and microbes, with particular relevance to tryptophan-derived AhR ligands [50, 51]

Edison, and Aravind Madhavan

V.TaylorR

Successful PROTAC design demands the concurrent optimization of multiple attributes, ternary complex stability, cellular permeability, pharmacokinetics, and tissue selectivity, a challenge for which AI is uniquely suited given its capacity to process high-dimensional, heterogeneous datasets [280, 281]