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Therefore, unlike with reduced folates where intestinal absorption is followed by direct incorporation into the liver, some of the UMFA in the portal blood likely bypasses the liver to subsequently bind to folate receptors on peripheral tissues such as the kidney (58)

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While redox-mediated activation of Hsp33s and Get3s chaperone function is initiated by oxidation of specific stress-sensing cysteine residues, other proteins, such as E