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They help your nerves work better, help your body make red blood cells, and generally keep your body active

In cytarabine resistant acute myeloid leukemia (AML) cells, increased TCA cycle intermediates such as citrate, AKG, succinate, fumarate, and malate were associated with increased oxphos compared to sensitive cells (Farge et al., 2017)

Consequently, neuronal mitochondria must consume oxygen (O 2 ) at a disproportionately high rate to meet the brains energy needs (Alle et al., 2009)

The top 12 high abundance proteins were then removed by Pierce Top 12 Abundant Protein Depletion Spin Columns Kit (Thermo Fisher), and the protein concentration determined using the BCA kit according to the manufacturers instructions