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A murine study involving 250 mg/kg/daily AOD9604 and 1mg/kg/day HGH for 14 days reported that obese mice lost 28% and 40% of their body weight, respectively [21]

the elderly, strict vegetarians (i.e., vegan), and patients with malabsorption problems are more likely to become deficient

Since adipose tissue is responsive to endotoxins, bacterial translocation may provide a mechanism whereby the gut microbiome can modulate the adipose metabolome (for review, Kruis et al., 2014 23 ) and consequently exacerbate obesity and its related comorbidities