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however, one might speculate that it indicates placental dysfunction and altered signalling properties of rafts enriched with very-long-chain sphingomyelins and ceramides

Orehek, E

Clinical Presentation In acute acetaminophen overdosage, dose-dependent, potentially fatal hepatic necrosis is the most serious adverse effect

This indicates that, like RABGAP1 KD, its overexpression also changes the processing of APP in primary rat neurons, providing further evidence for the direct role of RABGAP1 in mediating endogenous APP trafficking and cleavage