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Methods: We implemented siRNA and adenovirus-mediated Ybx1 overexpression in primary human and mouse hepatocytes, as well as continuous hepatocytes, to investigate the effect of Ybx1 modulation on PPAR mRNA levels

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B., Appa, Y., Bhandarkar, S

They have realistic expectations: they are not expecting a return to the early dramatic phase of GLP-1 weight loss, but rather a renewed period of modest progress through what would otherwise be a flat curve