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Description

Zebrafish and CAM assays were carried out using three independent biological replicates, each comprising 10 embryos and 3 eggs per treatment group

It also modifies the immunosuppressive TME, promoting immune activation, suggesting that enhancing chimeric antigen receptor cell function may represent a potential strategy for glioblastoma therapy (101)

However, their biological activity has been evaluated in only a limited number of cell lines and primarily through single metabolic assays, which limits the ability to draw clear conclusions about their mechanism of action and therapeutic potential