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The average weight loss of 2-3 kg over 12 weeks, while statistically significant, is substantially less than results achieved with appetite-suppressing medications or intensive dietary interventions

To assess CD38 expression, we used HuMax-003 (FITC) (Janssen Pharmaceuticals), which binds a CD38 epitope distinct from that recognized by DARA ( g for 1 h at 4 C)