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mTOR pathway modulation Nitric oxide system interaction (NOS pathway) Growth hormone receptor upregulation VEGFR2-Akt-eNOS axis activation (angiogenesis, vascular stability) Src-caveolin-1-eNOS pathway (antioxidant, HO-1 induction) ERK1/2 signaling pathway (proliferation, migration, vascular tube formation) Anti-inflammatory macrophage polarization (M1M2 shift, TNF-/IL-6/IFN- reduction) Neuromodulation (stabilizes acetylcholine, dopamine, serotonin, GABA) Research Findings Preclinical research into gastrointestinal healing represents the most extensively studied application area

doi: 10.4103/1673-5374.253507 433 ZhangZYangJLZhangLLChenZZChenJOCaoYGet al

A total of 500-600 primary leaves were collected, immediately submerged in 2 L RNA stabilization solution (10 mL water-saturated phenol (pH 2 log 2 FC higher expression relative to epiphytic and late apoplastic conditions

doi: 10.1093/abbs/gmab022 145 LiuZ.RenZ.ZhangJ.ChuangC