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In all the above examples, the additional Cys is the resolving Cys, suggesting the reactive Cys must come first in order for the mutation to become fixed in the population

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Addition or removal of GABAergic spine synapses in close proximity glutamatergic synapses in dendritic spines of cortical neurons allow the control of excitatory inputs through shunting inhibition (Maccaferri, 2005) and modulation of calcium signaling by near coincident activation of the GABAergic and excitatory inputs impinging on a particular spine (Chiu et al., 2013