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Description

Surface modification of nanoparticles enables selective evasion of phagocytic clearance by distinct macrophage phenotypes

Moreover, our results indicate a morphological remodeling by increasing neurite outgrowth and activation of the anti-inflammatory defense by inhibition of the cytokine production in human macrophages after STW3-VI treatment

This differential expression of HMGB1 suggests its utility as a predictive biomarker for treatment response, holding substantial promise for clinical implementation (199)