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In addition, in studies on GLN metabolism, N6-methyladenosine (m 6 A) regulates GLN metabolism through modification of insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), which directly or indirectly promotes AML cell development and self-renewal, and higher levels of IGF2BP2 expression correlate with a poor prognosis for AML [53]

Kojic Acid & Tranexamic Acid: Lighten dark spots and reduce melanin production

More comprehensive approaches should be incorporated to elucidate specific immune signaling pathways involved and the interaction between gut microbiota, enteric nervous system and immune activation during IBS pathogenesis (Lazaridis and Germanidis, 2018)