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This leads to an overabundance of calcium ion (Ca 2 ) influx and subsequent excitotoxic neuronal injury, contributing to ototoxicity

Specifically, glutathione: Fights off toxins such as mercury in the liver and brain Regenerates vitamin C and E in the body for strong immune support Is essential for energy production and cell detoxification Improves protein and enzyme levels in the blood Protects and supports cellular function, especially in the liver (part of the immune system) Oxidative stress biomarkers such as glutathione can test for a variety of diseases (2)

doi: 10.1016/j.redox.2023.102643 76 HenrotinYKurzBAignerT

In a study by Zhou et al., erythropoietin pre-treatment significantly upregulated CXCR4 expression, altered surface molecule profiles, reduced adhesion to pulmonary capillaries, and decreased pulmonary retention