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and (4) determining which recombinant cell-specific binding moiety polypeptides exhibit the present invention also provides methods for evolving a vaccine delivery vehicle, genetic vaccine vector, or a vector component to obtain an optimized delivery vehicle or component that has, or confers upon a vector, enhanced ability to enter a selected mammalian tissue upon administration to a mammal

These macromers were then polymerized to form enzymatically degradable PEG hydrogels, with VEGF tethered via a non-degradable PEG linker, resulting in protein release only when the gel is degraded (Figure 2B)

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These findings align with previous research on BD, which highlighted mitochondrial dysfunction and its stronger correlation with neurons in genetically lithium-responsive patients [102]