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ACSL4 is responsible for the addition of CoA to free long-chain PUFAs, especially the synthesis of PE-containing arachidonic acid (AA)-CoA or adrenic acid (AdA)-CoA [40]

For induction of Castor1 overexpression, stable HEK293T cells harboring either the Mm-Castor1 or control pTRIPZ construct were treated with 0.2 g/mL doxycycline (S5159, Selleck) for 48 hours

This idea was further supported by finding that administration of atazanavir to Wistar rats resulted in a rise of serum bilirubin levels while having no effect on bilirubin levels in Gunn rats, a strain that lacks the ability to conjugate bilirubin (Figure 1C)

Postmortem diagnosis of invasive meningococcal disease