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The most common side effects are constipation and nausea

However, given the variability in timing, protocol structure, and patient selection in the included studies, the authors acknowledged that beneficial effects in specific subgroups cannot be excluded and highlighted the urgent need for standardized treatment approaches

Immediate managementafter needlestick or other bloodborne exposureincludes cleansing of wounds and mucousmembranes, determination of the natureof exposure, and post-exposure counselingas to the transmissibility of HCV and theimplications of transmission