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GHK-Cu (copper peptide) side effects reported in available literature include localized injection site reactions, mild systemic inflammation markers, and rare allergic responses

10.1016/j.mce.2016.08.005 Summary Keywords estrogen, testosterone, granulosa cells, theca cells, Sertoli cells, Leydig cells, signaling Citation Ipsa E, Cruzat VF, Kagize JN, Yovich JL and Keane KN (2019) Growth Hormone and Insulin-Like Growth Factor Action in Reproductive Tissues

The full spectrum of peptides discussed in this guide is relevant

This results in downstream signaling responses such as intracellular second messenger activation or ion channel opening