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Notably, mice can experience hearing loss beyond normal levels in old age, even when exposed to acoustic environments that cause only transient hearing threshold shifts (Keithley, 2020)

Note that there are also perfusion MRI methods that use the blood as an endogenous perfusion marker

This process involves the activation of a cascade of caspase enzymes, particularly caspase-3, which executing apoptosis through the cleavage of key intracellular substrates