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In a mouse model of colorectal cancer, an expanded population of systemic and splenic cytotoxic T cells and reduced tumor burden were observed after vaccination with hAEC (165)

6a and Supplementary Fig

Human 41BB (CD137) signals are mediated by TRAF2 and activate nuclear factor-kappa B Biochem Biophys Res Commun 1998 242 : 613620 Ling L, Cao Z, Goeddel DV