glutathione and brain cancer Roles of selenium-containing peroxidases thioredoxin reductases in the regulation of processes associated with glioblastoma progression Glutathione-mediated nanomedicines for cancer diagnosis

Active targeting involves the attachment of ligands to the surface of nano systems (165, 166) to enhance their interaction with proteins that are consistently expressed at the blood-brain barrier, including the insulin receptor, transferrin (Tfr) (167), and low-density lipoprotein receptor (168, 169)

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The formation of carbonyl groups within the structure of amino acid side chains can result in protein inactivation and the subsequent accumulation of protein aggregates