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coli demonstrate increased permeability and destabilization of the TJ proteins ZO-1, occludin, and claudin-1 [84]

Vet J Lond Engl 204:322326 Verbeke J, Van Poucke M, Peelman L, De Vliegher S (2015c) Differential expression of CXCR1 and commonly used reference genes in bovine milk somatic cells following experimental intramammary challenge

INTERACTIONS OF ABSORPTION The first pharmacokinetic step absorption occurs in the stomach and small intestine and can be affected by numerous factors, including gastric pH, activity of the mucosal transport proteins (such as P-glycoprotein), gut microbial flora and gastrointestinal motility