glutathione transferase mechanism of action Homeostasis and Functions: Potential Targets for Medical Interventions - Lushchak - 2012 - Journal Amino Acids The catalytic role of glutathione

Association of iron overload and oxidative stress with insulin resistance in transfusion-dependent -thalassemia major and -thalassemia/HbE patients

One such drug is ramucirumab developed by Imclone LLC/Eli Lilly & Co

Given that several further dual agonists are coming closer to becoming licenced, such as mazdutide and survodutide, with many more in development [15], combining licenced dual agonists with developing mono-agonists may be a faster way to develop effective treatments achieving triple agonism

First, the structure information will allow researchers to design various versions of SLC7A11 mutants (which, e.g., lack the ability to import cystine or do not interact with erastin or SLC3A2) for future functional investigations of ferroptosis