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Jiao et al., 2012) The ability of PQ to induce loss of DA neurons in SNpc in vivo is sometime equivocal and reproducibility of the finding is representing an uncertainty (Smyne et al., 2016)

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They can also provide guidance on the correct dosage and duration of supplementation

Some of the downregulated lipid metabolism genes are involved in steroid biosynthesis, which may contribute to the downregulation of the steroid hormone response in both tissues