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Discussion Testicular ischemia induces germ cell apoptosis because of hypoxia and intracellular ATP depletion, and metabolic imbalance promotes the accumulation of harmful metabolites

Initiation of the chain reaction of lipid peroxidation requires the spark provided by the reduction of Fe +3 to Fe +2 using a single electron provided by the O 2 - (superoxide anion radical) formed during oxidative respiration in mitochondria