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Obesity is a chronic relapsing disease process, attributable to the complex interaction between genes and environmental risk factors, characterised by excess adiposity, that adversely impairs health [13]

Many anecdotal protocols range between 2001000 mcg per day, but individual needs differ

Notably, the lower weight loss (-13.7%) observed in REDEFINE 2 among individuals with T2D suggests that the magnitude of benefit achieved with combined GLP-1 and amylin receptor agonism may depend on the underlying metabolic status, highlighting the need for a more nuanced understanding of the mechanisms governing treatment response [13]

The two tools sit at different layers of a DAST stack