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Additionally, microRNAs (miRNAs) and suppressor of cytokine signaling 1 (SOCS1) (Gui et al., 2011) can control hepatocarcinogenesis by regulating HGF/c-Met

Pharmacological or gene inhibition of glutathione transporters, including multidrug resistant protein 1, can block cell GSH release, reduce intracellular ROS levels and production of oxidized phosphatidylcholine, thereby inhibiting cell ferroptosis