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[DOI] [PubMed] [Google Scholar] Berlin 1968 Berlin H, Berlin R, Brante G

Since in vitro studies showed 5-amino-1MQ to have high cell permeability, enzyme selectivity, and cell culture efficacy, a sub-chronic (11-day) proof-of-concept in vivo study was conducted to test the effect of NNMT inhibition on obesity in HFD fed mice