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From the synovial microvessels, small solutes diffuse through the extracellular matrix of the synovial intima to reach the intraarticular space ( , constituents and metabolites were detected in synovial fluid samples of osteoarthritis patients undergoing knee arthroplasty (see section 5.2 Distribution into blood cells) (Table 2)

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put forth a newly discovered interaction between galectin-3 (Gal-3) and cystinosin to explain the selectivity of renal tubular cells and the inability of cysteamine to halt the progression of kidney disease [41]

Although it does not reflect uptake metabolism in vitro, hepatoprotective and antioxidant effects were also verified in vivo