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Scientific Communications: acute 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.01 - ACUTE MANAGEMENT - Neither thrombolysis nor thrombectomy O - ESOC25-300 SYSTEMATIC REVIEW AND META-ANALYSIS ON MORTALITY AND FUNCTIONAL OUTCOME IN PATIENTS WITH LARGE CEREBELLAR INFARCTION TREATED WITH NEUROSURGERY Myriam Perla Mazloum 1 , Alberto Coccia 1,2 , Julien Labreuche 3 , Fabien Almairac 4 , Hilde Henon 5 , Barbara Casolla 1 1 Universit Cte d'Azur, UR2CA-URRIS, Unit Neurovasculaire, CHU Hopital Pasteur 2, Nice, France, 2 SC Neurologia con centro ictus, ASL 2 Liguria, Ospedale Santa Corona, Pietra Ligure, Italy, 3 Department of Biostatistics, CHU Lille, Lille, France, 4 Universit Cote d'Azur UR2CA-PIN, Neurosurgery Department, Pasteur 2 Hospital, Nice, France, 5 Lille University Hospital, Lille, France Background and Aims: Management of large cerebellar infarctions with potential malignant evolution is highly heterogenous across physicians

doi: 10.1016/j.ijbiomac.2017.10.016, 97

Larger scale studies may help to determine the clinical impact of NAC on measures of functioning over the course of illness, as well as the most effective dosage and dosage regimen

10.1074/jbc.m602413200 J Biol Chem