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revealed that prolonged intake (90 days) of high concentrations of green tea catechins (5%) brought about hepatotoxic effects in male rats by the increased levels of ALT and AST 48 , which could suggest that the use isolated or pure polyphenols could be detrimental to the functioning of these organs

Persistence in skin lesions in EM and ACA may be due to immune evasion [86], biofilms protecting the organism [68,87], as well as invasion of human skin fibroblasts by B