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If clinical signs like increased IOP have already developed, but there are still no noticeable symptoms, it is even more important to act quickly to prevent disease progression

This molecular pathway may be influenced by the level of daily physical activity, as a study using high-throughput sequencing found that physically fit individuals had higher fecal butyrate levels, better VO2 max values, more diverse gut microbiota, lower LPS biosynthesis, and consequently, less systemic inflammation [22, 44]

PLOS ONE 8, e75548

While it is disappointing this work was not reflected in performance improvement in the year, we are confident that it will translate into future environmental performance. The annual report said there were no quick fixes