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doi: 10.3389/fbioe.2025.1729166 Received 21 October 2025 Revised 01 December 2025 Accepted 17 December 2025 Published 15 January 2026 Volume 13 - 2025 Edited by Ling Wang, Dalian Medical University, China Reviewed by Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Updates Copyright 2026 Hu, Li, Hu, Shan, Tang, Jiang, Yi, Chen, Jin, Wang and Wang

GHK-Cu Dosage for Hair: Topical Protocol The most common GHK-Cu for hair protocol uses a topical serum applied directly to thinning areas of the scalp: Concentration: 25% GHK-Cu in a carrier serum (often with propylene glycol or liposomal delivery for penetration) Amount per application: 12 mL applied to affected scalp areas, massaged in for 60 seconds Frequency: Once or twice daily

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