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[2], [4] Retro-inverso peptides (also referred to as D-retro-inverso or DRI peptides) are specially engineered molecules in which the amino acid sequence is reversed and composed of D-amino acids, which are mirror images of the naturally occurring L-amino acids

Angeliki PK, Karyofyllis T, Paramithiotis D, Katerina K, Panos NK

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Professor Sikirics research contributions include: Initial isolation and characterization of BPC-157 from human gastric secretions Extensive investigations of gastroprotective and multi-organ tissue healing mechanisms Pioneering studies on musculoskeletal tissue repair including tendon, ligament, and muscle healing Research on cardiovascular protective effects and vascular injury healing Investigations of BPC-157 interactions with nitric oxide pathways and growth factor systems Over 100 published papers examining BPC-157s pleiotropic effects across organ systems His work has established BPC-157 as one of the most comprehensively studied components in peptide-based regenerative research, though human clinical validation remains completely absent