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Fibroblast-like synoviocytes: key effector cells in rheumatoid arthritis

1079-A HIGHER PLATELETS LEVELS IN POSTOPERATIVE ORTHOTOPIC LIVER TRANSPLANT PATIENTS ASSOCIATED WITH HIGHER RATES OF COMPLICATIONS Emily E Currier 1 , Arif Sarowar 1 and Syed-Mohammed Jafri 2 , (1)Wayne State University, (2)Henry Ford Health System Background: Prior research into the relationship between liver transplant outcomes and platelet levels is limited, but research has shown that peri-operative thrombocytopenia is linked to decreased outcomes and thrombocytopenia on postoperative day 5 have been linked to higher 90-day mortality

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Specifically, cytokines secreted by Th1 and Treg cells (e.g., IFN-, IL-2) decrease, while those from Th2 and Th17 cells (endocrine IL-1, IL-4, IL-6) increase, suppressing immune function and promoting apoptosis (150)