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Specifically, KEGG pathway enrichment analysis revealed significant associations with glutathione metabolism, a pathway associated with neurodegenerative diseases [26]

The ferroptosis activator RSL-3 and the PI3K/Akt pathway inhibitor LY294002 reversed Neuritins inhibitory effect on ferroptosis, indicating that Neuritin suppresses neuronal ferroptosis via PI3K/Akt pathway activation (Song et al., 2025)

Glutathione reductase from pea leaves: response to abiotic stress and characterization of the peroxisomal isozyme

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