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The administration of GHRH in healthy non-obese older men shows statistically significant elevated HGH levels and a dose-dependent increase of IGF-1 concentration, reversing their age-related declines (Vittone et al., 1997)

Epithalon (longevity potential) Article: Epithalon studied for longevity and cellular health Epithalon is a synthetic peptide modeled after pineal gland compounds that may activate telomerase to maintain DNA telomeres, support circadian rhythms and melatonin production, though human research remains limited and mostly preclinical