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Cardiac excitationcontraction coupling

Irregular meal times or eating during the biological night can desynchronize peripheral clocks from the SCN, contributing to internal misalignment

During conditions of stress, when NO or carbon monoxide (CO) levels rise, causing inhibition of CBS due to the formation of nitrosyl or ferrous carbonyl CBS, homocysteine accumulates, leading to the production of H 2 S by CSE (Banerjee, 2017)