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Note: The heterotrimeric G proteins discussed here should be distinguished from the small, low molecular weight, monomeric G proteins of the Ras, Rab, Rho, etc

Below are highlights from the most significant published studies

There are theoretically hundreds of thousands of these peptides, Cohen says

Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/connective tissue growth factor angiogenic inhibitory complexes by MMP-2 proteolysis