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In contrast, inflammatory eosinophils III showed reduced expression of both immediate early response and inflammatory genes, while upregulating mitochondrial genes ( mt-Co3 , mt-Nd1 ), suggesting enhanced mitochondrial activity

Moreover, a recent study showed that Nrf2 deficiency in bone marrow cells aggravates metastasis (Satoh et al., 2010)

Grx activity was determined by monitoring the consumption of NADPH at 340 nm during the GSH-dependent reduction of 8 mM -hydroxyethyl disulfide (HED) using 1 mM GSH coupled with of 0.6 units of yeast GR (Sigma) [20]