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However, it should be one factor among many in the evaluation process

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Protein Cell (2010) 1(10):88897

To evaluate if knockout of ABCC1 also enhances the anti-leukemic effects of AZD-4320 in vivo, we transplanted equal numbers of MOLM-13 AAVS1.1 control or ABCC1 -knockout cells into NSG-S mice and treated them once a week with either AZD-4320 (10 mg/kg) or vehicle