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Key finding: AOD 9604 increased type II collagen synthesis by 180% and cartilage proteoglycan content by 156% in human OA chondrocytes

We discussed and solicited comment on the circumstances in which we would exercise our discretion to reopen a payment determination and issue a revised initial determination to account for the impact of identified improper payments on Shared Savings Program calculations (described in section III.G.7.c.(2).(b) of the proposed rule)

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