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Gain-of-function studies demonstrated that recombinant BDNF mimics might have beneficial effects on NSC transplantation, while loss-of-function studies showed that mice depleted of NSC-derived BDNF failed to improve cognition or restore hippocampal synaptic density (80)

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[DOI] [PubMed] [Google Scholar] 21.Turner DS, Etheridge L, Jones J, Marks V, Meldrum B, Bloom SR, et al

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