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elegans and mice showed that EGCG's transient inhibition of Complex I in the electron transport chain triggered an adaptive stress response (mitohormesis) that ultimately restored ATP levels, reduced reactive oxygen species below baseline, and significantly extended lifespan and physical fitness

1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol attenuates streptozotocin-induced pancreatic beta cell damage by promoting glucose transporter 2 endocytosis

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Enzymes supporting phase 2 detoxification reactions, such as those involved in the biosynthesis of glutathione (e.g., -glutamylcysteine synthetase or GCS) and its conjugation to substrates (e.g., glutathione S -transferases or GSTs), are rapidly induced following exposure to stressful stimuli