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Accordingly, it is preferred that the copolymer (C-2) in the first coating comprises methacrylic acid repeating units and methyl methacrylate repeating units in a molar ratio of 1 :1.5 to 1 :2.5, more preferably in a molar ratio of 1 :2

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Subclinical atherosclerosis and impaired cardiac autonomic control in pediatric patients with vitamin B12 deficiency