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Animal studies administering 5-Amino-1MQ orally to diet-induced obese mice have shown dose-dependent reductions in body weight (typically 10-30% reduction compared to vehicle-treated obese controls over 4-12 week treatment periods), with the weight loss primarily reflecting fat mass reduction while lean mass is preserved or even increased

Clinical and genetic keys to cerebellar ataxia due to FGF14 GAA expansions

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Optimal dosing for neuropathy applications is extrapolated from general tissue repair protocols rather than neuropathy-specific dose-finding studies for most peptides