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Besides the well-known FGF21, pregnancy zone protein (PZP) produced from the liver binds to glucose-regulated protein of 78 kDa on cell membrane of the BAT, subsequently, promotes diet-induced thermogenesis by inducing uncoupling protein 1 (UCP1) expression through a p38 MAPK-ATF2 signaling pathway

in 2024 reported from Spain the antiaging effects of custom low-molecular-weight collagen peptide supplementation (2.5 g) on facial wrinkles and skin hydration in a 6-week randomized, double-blind, placebo-controlled trial [46]

The KD was also found to reduce the volumes of soluble amyloid-beta in homogenates of murine brains (141)

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Li H., Feng J., Liu C., Hou S., Meng J., Liu J.Y., Zilong S., Chang M.C